Least sedating benzodiazepine

The half-life of Temazepam is approximately 10 hours (varies from person to person), making it appropriate for treatment of sleep maintenance insomnia. There is a significant risk of dependence for people taking temazepam. Lormetazepam (C16H12Cl2N2O2) is a benzodiazepine that can be used for insomnia. It is pretty powerful and not appropriate for most people with sleep disorders when other drugs will work for them.* The major disadvantage is the long half-life, which causes the patient to experience daytime sleepiness or trouble getting up the day after swallowing the pill.Although diazepam is approved to treat anxiety, panic attacks, and insomnia (short-term), many of its uses are off-label; including tetanus, mania, alcohol and opiate withdrawal, spastic muscle paresis, and as pre- or post-operative sedation.Frequent side effects include impaired motor function, anterograde amnesia, and depression.Roche manufactures nitrazepam and it is sold in the U. It is also used to treat insomnia where the individual has difficulty staying asleep.Oxazepam produces many common side effects: drowsiness, dry mouth, dizziness, fatigue, weakness, and diarrhea.It is indicated for the treatment of anxiety disorders, short-term insomnia (especially when it is associated with anxiety), acute delirium, several types of epilepsy, and as a pre-medication to decrease the quantity of an anesthetic required before a surgical procedure.It is also used to combat the nausea and vomiting associated with chemotherapy.

Benzodiazepines (sometimes called in the scientific literature, Bz RAs) have a much lower ratio and very rarely led to fatal overdoses.

Flunitrazepam is marketed in many other countries by Roche as Rohypnol®.

Its use produces many side effects, among them drowsiness, loss of motor control, amnesia, slurred speech, and confusion.

Sometimes they are used to neutralize the anxiety-related symptoms that may accompany the initial use of selective serotonin reuptake inhibitors (SSRIs) and other antidepressants.

Bz RA potentiate the effects of GABA, but have little direct effect on other neurotransmitters.

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Benzodiazepines receptor agonists (Bz RAs) are a group of prescription drugs that slow down the body’s central nervous system (CNS).

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